Preheat Oven: Preheat your oven to 350°F (175°C) and grease a 9x5-inch loaf pan or line it with parchment paper.
Prepare the Cream Cheese Filling: In a medium bowl, beat the softened cream cheese, powdered sugar, egg, gluten-free flour, vanilla extract, and almond milk until smooth. Set aside.
Mix the Wet Ingredients: In a large bowl, whisk together the pumpkin puree, avocado oil, melted butter, almond milk, whisked eggs, granulated sugar, brown sugar, and vanilla extract until fully combined.
Mix the Dry Ingredients: In a separate bowl, whisk the gluten-free flour, pumpkin pie spice, cinnamon, baking soda, baking powder, and sea salt.
Combine Wet and Dry Ingredients: Gradually stir the dry ingredients into the wet mixture until just combined. Do not overmix.
Assemble the Bread: Pour half of the pumpkin bread batter into the prepared loaf pan and smooth the top. Spread the cream cheese filling evenly over the batter. Then, add the remaining pumpkin batter on top of the cream cheese layer and smooth it out.
Bake: Bake for 55-65 minutes, or until a toothpick inserted into the center comes out clean.
Cool: Allow the bread to cool in the pan for 10-15 minutes before transferring it to a wire rack to cool completely.